P r o g r a m m e
DAY ONE
Tuesday April 28, 2026
13.30 – 14.30 Welcome and Registration
14.30– 14.45 Opening Ceremony
Prof. Angelo Antonio Izzo, Director, Department of Pharmacy, University of Naples Federico II
Prof. Concetta Giancola – President, Campania Section, Italian Chemical Society (SCI)
Dr. Sveva Pelliccia – Conference chair
Dr. Vincenzo Piccolo – Conference Co-Chair
14.50-15.50: Plenary lecture - Prof. Klaus Kümmerer, Director of the Institute of Sustainable Chemistry at Leuphana University Lüneburg, Germany - "Pharmaceuticals in the Environment: From a Problem to a Business Opportunity Through Benign by Design"
16.00-17.30: SESSION 1 Sustainable Valorisation of Natural Bioactives for Human Health
Chairpersons: Cinzia Pezzella – Severina Pacifico
OC 01: Comune Lara – University of Campania Luigi Vanvitelli (Caserta, Italy) - "Polyphenol-Enriched Alginate Beads from Ravece cv. Olive Leaves and Olive Oil for Functional Use"
OC 02: Aquino Giovanna - AREA Science Park (Trieste, Italy) - "Unlocking Nutraceutical Value from Agri-Food By-Products: A Sustainable Waste-to-Wellness Strategy Within the Circular Bioeconomy Framework"
OC 03: Diglio Carmen – University of Campania Luigi Vanvitelli (Caserta, Italy) - "Edible Feijoa Flowers: Polyphenolic Profiling and Functional Coating"
OC 04: Dzhambariva Ivelina Ivaylova – University of Naples Federico II (Napoli, Italy) - "Think Pink: From Bioprocess Optimization to HDES-Microemulsion for Bacterioruberin Delivery"
OC 05: Fydrych Dagmara – Nicolaus Copernicus University in Toruń (Bydgoszcz, Poland) - "Evaluation of Antimicrobial and Antibiofilm Activity of Gallic Acid, Quercetin-3-D-Glucuronide and Apigenin Against Gram-Negative Uropathogens"
OC 06: Mucci Lucia – University of Campania Luigi Vanvitelli (Caserta, Italy) - "Turning Vineyard Waste into Functional Gold: Quercetin 3-O-Glucuronide from Aglianico Vine Leaves as a Natural Antioxidant Colorant"
OC 07: Angelino Simona – University of Naples Federico II (Napoli, Italy) - "New Diamine-Mediated Pathway for Polyphenol-based Functional Coatings"
OC 08: Jeziurska-Pavlenko Jagoda – Nicolaus Copernicus University in Toruń (Bydgoszcz, Poland) - "Study of the impact antibiotic combinations used in urinary tract infections on the effectiveness of antimicrobial therapy"
OC 09: Palmieri Roberta – University of Campania Luigi Vanvitelli (Caserta, Italy) - "Cellulose Extraction from Grapevine Pruning Residues: A Gate-to-Gate Life Cycle Assessment at Laboratory Scale"
17.30-18.30: Welcome Cocktail
DAY TWO
Wednesday April 29, 2026
09.30-11.00: SESSION 2: Sustainable Nanocarriers and Green Strategies for Advanced Drug Delivery
Chairpersons: Giuseppe Floresta – Gabriella Costabile
KN 1: Dr. Adrian Matencio Duran, University of Murcia (Murcia, Spain) - "From Nutraceuticals to Pharmaceuticals: Molecular Strategies for Bioactive Delivery"
OC 10: D'Anna Pasquale – University of Naples Federico II (Napoli, Italy) - "Cationic Amphiphilic Hybrid System for siRNA-Based Combination Strategy in Triple-Negative Breast Cancer"
OC 11: Piccolo Virgilio – University of Naples Federico II (Napoli, Italy) - "Nanoparticles based on inulin and polyesters for the delivery of siRNA and Docetaxel to solid tumors"
OC 12: Sguizzato Maddalena – University of Ferrara (Ferrara, Italy) - "Cyclodextrin nanosystems for Rutin oral delivery: a "dual-carrier" strategy for diabetic dietary supplementation"
OC 13: De Cristofaro Ilaria – University of Naples Federico II (Napoli, Italy) - "Ionizable Lipid-based Nanocarriers for Targeted siRNA delivery"
OC 14: Molaro Maria Cristina – University of Naples Federico II (Napoli, Italy) - "PISA-Engineered Polymeric Nanoparticles for the Targeted Delivery of FS536, a Doxorubicin–Nitric Oxide Hybrid with Anti-MDR Activity"
OC 15: Spirito Alessandra – University of Naples Federico II (Napoli, Italy) - "Development and Clinical Evaluation of a Buccal Nanoemulsion for Enhanced Cannabinoid Delivery in Chronic Pain Management"
11.15-11.45: Coffee break
11.45-13.00: SESSION 3: Sustainable Platforms, Functional Materials, and Controlled Release Systems
Chairpersons: Claudia Conte- Thomas L. Moore
OC 16: Patamia Vincenzo – University of Catania (Catania, Italy) - "Multi-modal bio-platforms: harnessing natural architectures for advanced surface preservation and biosafety"
OC 17: Di Spirito Nicola Antonio – University of Naples Federico II (Napoli, Italy) - "Pluronic F68 as a Versatile Platform for Sustainable and Functional Drug Delivery Systems"
OC 18: Imbò Lorenzo Emiliano – University of Naples Federico II (Napoli, Italy) - "Engineering myxinidin-based supramolecular architectures for advanced antifungal applications in food protection"
OC 19: Perinelli Diego Romano – University of Camerino (Camerino, Italy) - "Zein-based natural layered biodegradable films for food bio-packaging applications"
OC 20: Marra Sebastiano – University of Naples Federico II (Napoli, Italy) - "Mesoporous vs Wrinkle Silica Nanoparticles: Architecture Driven Loading of Luminescence Ruthenium complexes for Photodynamic Therapy"
OC 21: Trucillo Paolo – University of Naples Federico II (Napoli, Italy) - "Graded foamed tablets as tunable delivery systems"
13.00-13.20: Sponsor Presentation: SP 1: TILRAY – Title TBA
13.20-14.30: Lunch & Poster Session
14.30-14.50: Sponsor Presentation: SP2: Dr. Daniela Iaconis, Dompé Farmaceutici S.p.A. – "AI-Driven Drug Discovery: From Chemical Space Exploration to Experimental Validation"
14.50-16.30: SESSION 4: Computational Chemistry and Artificial Intelligence for Sustainable Drug Discovery
Chairpersons: Antonella Ciancetta - Rino Ragno
KN 2: Dr. Nicola Gambacorta, University of Bari Aldo Moro (Bari, Italy) - "Navigating Chemical Space: Integrated in Silico Platforms for Next-Generation Drug Discovery"
OC 22: Astolfi Roberta – Sapienza University of Rome (Roma, Italy) - "Computational Approaches for the Identification of Novel DYRK1A Inhibitors: Machine Learning, 3-D QSAR, Docking Assessment, and ComBinE Analysis"
OC 23: Delre Pietro – University of Naples Federico II (Napoli, Italy) - "VeGA: A Versatile Generative Architecture for Bioactive Molecules across Multiple Therapeutic Targets"
OC 24: Astolfi Andrea – University of Perugia (Perugia, Italy) - "Toward Sustainable Antibiotic Adjuvant Discovery: An In Silico-to-Experimental Strategy Targeting NorA"
OC 25: Bellofatto Giada – University of Naples Federico II (Napoli, Italy) - "From Apo to Ligand-Bound: Unraveling PPARγ-LBD Conformational Shifts via Advanced Molecular Dynamics"
OC 26: Mastrolorito Fabrizio – University of Bari Aldo Moro (Bari, Italy) - "fragSMILES to express chemical fragments and chirality for synthesis planning"
OC 27: Di Giovanni Carmen – University of Naples Federico II (Napoli, Italy) - "Exploring human sperm nuclear basic protein–DNA interactions: a combined experimental and computational study on hexavalent chromium interference"
16.30-17.00: Coffee break
17. 00-17.20: Sponsor Presentation: SP 3: AVEXTRA – Title TBA
20.00: Social aperitif AT BARRIO BOTANICO (Via A. Scarlatti 139, Napoli)
DAY THREE
Thursday April 30, 2026
9.00- 10.30: SESSION 5: Green Technologies for Sustainable Drug Synthesis and Optimization
Chairpersons: Giuseppe La Regina - Beatrice Severino
KN3: Prof. Margherita Brindisi, University of Naples Federico II (Napoli, Italy) – "Rethinking the generation of privileged scaffolds in medicinal chemistry using continuous flow, mechanochemistry and paper-based platforms"
OC 28: Merlino Francesco – University of Naples Federico II (Napoli, Italy) - "Sustainable Ultrasound-Assisted Solid-phase Synthesis of Bioactive Peptides"
OC 29: Fontana Anna – University of Pavia (Pavia, Italy) - "Mechanochemical synthesis of 2,3- dihydroquinazolin-4(1H)-one derivatives via mortar-pestle grinding approach"
OC 30: Martina Maria Grazia – University of Parma (Parma, Italy) - "Green Enabling Technologies for the Optimization of Novel Small-Molecule PCSK9 Inhibitors with Multiple Pharmacological Applications"
OC 31: Rossitto Emanuele – University of Bari Aldo Moro (Bari, Italy) - "High-Efficiency Mechanochemistry: evolution of sustainable routes to TRPM8 antagonists"
OC 32: Alfano Antonella Ilenia – University of Naples Federico II (Napoli, Italy) - "Flowing Light for Green Pinacol Coupling of Aldehydes and Imines"
10.30 -11.00: Coffee break
11.00-11.20: Sponsor Presentation: SP 4: Dr. Callipo Luciano, Agilent Technologies, Inc. - "Orthogonal Separation of Pharmaceutical Impurities by the Agilent 1260 Infinity III SFC/UHPLC Hybrid System"
11.20- 12:00: SESSION 6: Safe and Sustainable by-Design Strategies for Novel Therapeutics
Chairpersons: Giuseppe La Regina – Beatrice Severino
OC 33: Marchetti Filippo – University of Ferrara (Ferrara, Italy) - "A Safe-and-Sustainable-by-Design chemo-enzymatic platform for novel ophthalmic therapeutics: development of hyaluronic acid-biosteroids hybrid system"
OC 34: Piazza Filippo – University of Bologna (Bologna, Italy) - "Harnessing multicomponent reaction for developing sustainable antiviral hits starting from CNSL"
OC 35: Rotili Gabriele – Sapienza University of Rome (Roma, Italy) - "A selective hCA IX/XII inhibitor targeting the Wnt/β-catenin signaling pathway, and P-gp: a novel polypharmacological compound"
OC 36: Zurzolo Simone – University of Siena (Siena, Italy) - "From Solid Waste to Catalysis"
12.00-12:30: Awards ceremony and closing remark